Notre Dame closes its 2026 regular season with a trip to the JMA Wireless Dome in Syracuse on November 28, 2026. The series between the Irish and Orange dates back more than a century to their first meeting in 1914, and while it has been sporadic over the decades, matchups have often garnered attention due to memorable moments and Syracuse’s long regional profile in the Northeast. This road fixture continues Notre Dame’s longstanding Atlantic Coast Conference schedule rotation.

On the field, Notre Dame holds the all-time series advantage against Syracuse, 9-3, with the Irish winning six straight meetings through 2025. The most recent matchup came on November 22, 2025, when Notre Dame delivered a dominant 70-7 victory in South Bend, marking one of the program’s most lopsided wins in the series. That result extended Notre Dame’s control of the series and underscored its performance against an ACC opponent. The 2026 contest adds another chapter to a rivalry with deep historical roots and a modern run of Irish success.